Custom Peptides
Cayman Chemical Mn IIITBAPchlorIde 10mg
Mn(III)TBAP is a cell-permeable SOD mimic. At a concentration of 30 µM, it decreases the doubling time of SOD-null E. coli. by 2-fold.{4009}
Cayman Chemical CnabInol methyl ether 10mg
A phytocannabinoid whose physiological and toxicological properties are not known
Cayman Chemical 14-TrIamcInolon acetonIde 10mg
A potential impurity found in commercial triamcinolone acetonide preparations
Cayman Chemical LInoleoylLcarnItInchLRI 10mg
A long-chain acylcarnitine; levels are increased following high-dose (200 mg/kg) administration of isoniazid in mice
Cayman Chemical LuteolosIde 10mg
A flavanoid with diverse biological activities; reduces LDH and caspase-3 activities and production of ROS and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury; blocks 3C protease activity (IC50 = 0.36 mM); reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM); inhibits the growth of HCC cells in vitro and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model at 2 mg/kg; reduces acanthosis and expression of epidermal differentiation markers in a mouse model of imiquimod-induced psoriasis
Cayman Chemical Coprostnol 10mg
A cholesterol derivative; formed via conversion of cholesterol to cholestenone then coprostanone intermediates or by direct reduction of the 5,6 double bond; commonly used as a marker of sewage contamination in soil and watersheds
Cayman Chemical TIaprofenIc AcId 10mg
A COX inhibitor and NSAID with anti-inflammatory and analgesic activities; inhibits synthesis of PGE2 and PGF2α from arachidonic acid in bovine seminal vesicle microsomes and inhibits TXB2 formation in human umbilical cord arteries bathed in clotting human blood (IC50 = 0.71 μM); has anti-inflammatory activity in rat models of carrageenan-induced edema and adjuvant-induced arthritis and has analgesic activity in acetic acid- or phenylquinone-induced writhing tests in rodents
Cayman Chemical JQKD82hydrochlorIde 10mg
A prodrug form of KDM5-C49; increases the levels of H3K4me3 in MOLP-8 and MM.1S cells at 0.3 and 1 µM; reduces the proliferation of MOLP-8 and MM.1S cells in a concentration-dependent manner; decreases the viability of primary CD138+ cells from patients with multiple myeloma at 3 µM; induces cell cycle arrest at the G0/G1 phase, as well as induces apoptosis, in MOLP-8 and MM.1S cells at 1 µM; decreases tumor growth and increases survival in a MOLP-8 mouse xenograft model at 50 mg/kg twice per day
Cayman Chemical Pogostmons hrba Pogoston 10mg
A pyranone with antifungal and insecticidal activities; active against a laboratory strain and clinical isolates of C. albicans (MICs = 49 and 12-97 UG/ml, respectively); reduces fungal load in the vagina in a mouse model of fluconazole-resistant vulvovaginal candidiasis at 1, 2, and 4 mg/kg per day topically or 20, 40, and 80 mg/kg per day orally; toxic to S. exigua and S. litura larvae with LC50 values of 545.61 and 986.88 mg/L for dietary administration and 519.48 and 1,041.42 mg/L for contact application
Bachem (D-Ala2)-Gastric Inhibitory Polypeptide (human) Trifluoroacetate
(D-Ala2)-Gastric Inhibitory Polypeptide (human) Trifluoroacetate, H-Tyr-D-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH, 444073-04-5, C226H338N60O66S, Mr 4983.53, 0.5mg. (D-Ala2)-GIP (human), [DAla2] Gastric Inhibitory Peptide (GIP), human. GIP receptor agonist.
Cayman Chemical CP 93 129hydrochlorIde 10mg
A 5-HT1B receptor agonist; selectively binds 5-HT1B over 5-HT1A, 5-HT1C, 5-HT1D, and 5-HT2 (Kis = 0.0081, 1.5, 2.9, 1.1, and 7.2 µM, respectively); inhibits potassium-induced GABA release from rat globus pallidus slices at 5.4 µM; reverses reserpine-induced akinesia in a rat model of Parkinson's disease at 110 and 220 nmol/animal; reduces food intake in rats when infused into the pons parabrachial nucleus or the PVN of the hypothalamus (ED50s = 1 and 50 nmol, respectively); reduces the frequency of pursuits, tail rattles, threats, and attack bites in a resident-intruder test in mice
Cayman Chemical N 8ZHeptadecen1ylO 3p 10mg
A synthetic macamide that irreversibly inhibits FAAH with an IC50 value of 0.153 µM